如何在传递给脚本之前从URL中删除子目录？

您需要重写uri而不会触发重定向,如使用中所述break.

根据您设置的详细信息,是否所有内容都应该发送到后端,或者Nginx是否应该提供某些请求(如静态文件),您需要...

location /store {
    try_files $uri @store_site;
}

location /backoffice {
    try_files $uri @backoffice_site;
}

location @store_site {
    rewrite  ^/store/(.*) /$1 break;
    include uwsgi_params;
    uwsgi_pass unix:/var/run/uwsgi/store_site.sock;
}

location @backoffice_site {
    rewrite  ^/backoffice/(.*) /$1 break;
    include uwsgi_params;
    uwsgi_pass unix:/var/run/uwsgi/backoffice_site.sock;
}

... 要么

location /store {
    rewrite  ^/store/(.*) /$1 break;
    include uwsgi_params;
    uwsgi_pass unix:/var/run/uwsgi/store_site.sock;
}

location /backoffice {
    rewrite  ^/backoffice/(.*) /$1 break;
    include uwsgi_params;
    uwsgi_pass unix:/var/run/uwsgi/backoffice_site.sock;
}